Description

1-Oleoyl-2-Methyl-Sn-Glycero-3-Phosphothionate (Ammonium Salt) is a specialized synthetic phospholipid derivative, a key building block in advanced lipid research and formulation. This compound is valued for its role in creating model membranes and liposomal delivery systems due to its unique thioester linkage and defined acyl chain profile. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced material science sectors for drug delivery, diagnostic imaging, and membrane biophysics studies.

Application

• Liposome and Nanoparticle Formulation: A critical component for constructing stable, functionalized lipid bilayers in targeted drug delivery systems.
• Biomembrane Research: Used as a model phospholipid to study membrane dynamics, protein-lipid interactions, and cellular signaling processes.
• Diagnostic Agent Development: Serves as a precursor or carrier for contrast agents and probes in medical imaging applications.
• Gene Delivery Vectors: Incorporated into cationic lipid mixtures to enhance the stability and transfection efficiency of non-viral gene carriers.
• Bioconjugation and Surface Modification: The reactive thioester group allows for covalent attachment of targeting ligands, peptides, or other functional molecules.
• Cosmetic and Dermal Delivery: Employed in high-end cosmetic formulations for creating nanocarriers that improve skin penetration of active ingredients.

Basic Information

Product Name	1-Oleoyl-2-Methyl-Sn-Glycero-3-Phosphothionate (Ammonium Salt)
CAS No.	799268-70-5
Molecular Formula	C23H48NO6PS
Molecular Weight	497.66 g/mol
Synonyms	1-Oleoyl-2-methyl-sn-glycero-3-thiophosphoric acid ammonium salt; (2R)-2-Methyl-3-(oleoyloxy)propyl hydrogen phosphorothioate ammonium salt; Ammonium 1-oleoyl-2-methyl-sn-glycero-3-phosphothionate; Phospholipid analog (thioester); Thio-phospholipid ammonium salt; sn-1-Oleoyl-2-methyl-glycerophosphothionate; OMPT (Ammonium Salt); Lipid research compound 799268-70-5
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-2-Methyl-Sn-Glycero-3-Phosphothionate (Ammonium Salt) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and formulation. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) principles for advanced intermediates and can support regulatory documentation needs for preclinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic and moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.