Description

Bis(Monooleoylglycero)Phosphate (S,R Isomer) (Ammonium Salt) is a high-purity, stereochemically defined phospholipid derivative, specifically the ammonium salt of the S,R isomer. This compound is critical for advanced research and development in lipid-based drug delivery systems, where precise molecular structure directly impacts biological activity and formulation stability. It is primarily sought by pharmaceutical R&D teams, formulation scientists, and manufacturers of liposomal and nanoparticle-based therapeutics.

Application

• Liposomal Drug Delivery: A key functional excipient for constructing stable, pH-sensitive liposomes for targeted cancer therapy and vaccine adjuvants.
• mRNA-LNP Formulations: Used as an ionizable or helper lipid component in lipid nanoparticle (LNP) systems for nucleic acid delivery.
• Biomembrane Research: A valuable tool for studying membrane dynamics, lipid-protein interactions, and intracellular trafficking mechanisms.
• Diagnostic Agent Carrier: Serves as a component in contrast agent or imaging probe carriers for enhanced biodistribution.
• Cosmetic Actives Delivery: Employed in high-end cosmetic formulations for the encapsulation and sustained release of active ingredients.
• Reference Standard: Used as an analytical standard in quality control and regulatory filing for complex lipid-based products.

Basic Information

Product Name	Bis(Monooleoylglycero)Phosphate (S,R Isomer) (Ammonium Salt)
CAS No.	799268-67-0
Molecular Formula	C39H78NO10P
Molecular Weight	752.01 g/mol
Synonyms	BMP (S,R Isomer) Ammonium Salt; (S,R)-BMP-NH4; Ammonium (S,R)-Bis(1-oleoyl-2-hydroxy-sn-glycero-3)phosphate; LBPA (S,R Isomer) Ammonium Salt; (S,R)-Lysobisphosphatidic Acid Ammonium Salt; 1,1'-Oleoyl-2-hydroxy-sn-glycero-3-phospho-sn-1'-glycerol (S,R Isomer) Ammonium Salt; BMP-NH4 (S,R); Lipid 18:1 BMP (S,R) Ammonium Salt
EINECS	Contact for details

Quality Control

Our Bis(Monooleoylglycero)Phosphate (S,R Isomer) (Ammonium Salt) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of regulatory filings (IND/NDA) and advanced therapeutic development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (S,R Isomer)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.