Description

1,2-Dihexanoyl-Sn-Glycero-3-Phospho-(1'-Myo-Inositol-3',5'-Bisphosphate) (Ammonium Salt) is a high-purity, synthetic phospholipid derivative of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P₂), a critical signaling lipid in eukaryotic cells. This compound serves as an essential biochemical tool for studying intracellular signaling pathways, membrane trafficking, and ion channel regulation. It is primarily utilized by researchers and developers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on cell biology, metabolic disorders, and novel therapeutic discovery.

Application

• Biochemical Research: As a defined substrate or standard for studying enzymes like phosphatidylinositol kinases and phosphatases in vitro.
• Lipid Signaling Studies: Investigation of PI(3,5)P₂'s role in endosomal sorting, autophagy, and cellular stress responses.
• Membrane Biophysics: Incorporation into lipid bilayers or liposomes to model membrane properties and protein-lipid interactions.
• Drug Discovery Screening: Use in high-throughput assays to identify modulators of PI(3,5)P₂-binding proteins and downstream effectors.
• Diagnostic Development: Potential use as a critical component in assay kits for quantifying specific lipid metabolites or enzyme activities.
• Cell Biology Reagents: Preparation of specialized delivery systems (e.g., lipid nanoparticles) for introducing signaling lipids into live cells.

Basic Information

Product Name	1,2-Dihexanoyl-Sn-Glycero-3-Phospho-(1'-Myo-Inositol-3',5'-Bisphosphate) (Ammonium Salt)
CAS No.	799268-61-4
Molecular Formula	C27H55N2O21P3
Molecular Weight	860.66 g/mol
Synonyms	PI(3,5)P₂ (C6:0); Dihexanoyl PI(3,5)P₂ ammonium salt; 1,2-Dihexanoylphosphatidylinositol 3,5-bisphosphate; Phosphatidylinositol 3,5-bisphosphate (C6:0); PtdIns(3,5)P₂ (diC6); 1,2-Di-O-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate); Ammonium 1,2-dihexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade biochemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing lot-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for all our lipid products.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere or desiccated conditions. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol/water mixtures
Water Content (KF)	< 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.