Description

3-(Phenylethynyl)Pyrazin-2-Amine is a high-purity, specialized heterocyclic building block featuring a pyrazine core substituted with an amine and a phenylethynyl group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Organic Electronic Materials: Serves as a precursor in the development of organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated system.
• Chemical Synthesis Scaffold: Employed in medicinal and combinatorial chemistry for creating diverse compound libraries via further functionalization of the amine and alkyne groups.
• Ligand Synthesis: Used in coordination chemistry to create novel ligands for catalysis and material science applications.

Basic Information

Product Name	3-(Phenylethynyl)Pyrazin-2-Amine
CAS No.	798544-32-8
Molecular Formula	C12H9N3
Molecular Weight	195.22 g/mol
Synonyms	2-Amino-3-(phenylethynyl)pyrazine; 3-(2-Phenylethynyl)pyrazin-2-amine; 2-Pyrazinamine, 3-(2-phenylethynyl)-; 798544-32-8; 3-Phenylethynylpyrazin-2-amine
EINECS	Contact for details

Quality Control

Every batch of 3-(Phenylethynyl)Pyrazin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA) including purity (typically ≥95% by HPLC), identity confirmation (by NMR and IR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.