Description

Cardiolipin (E. Coli) (Sodium Salt) is a high-purity, anionic phospholipid specifically sourced from Escherichia coli. This compound is essential for research and development in biochemistry and membrane biology, serving as a critical component for studying mitochondrial function, apoptosis, and autoimmune diagnostics. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on metabolic disorders and cardiovascular diseases. The product is supplied as the sodium salt for enhanced stability and solubility in aqueous systems.

Application

• Biochemical Research: Key substrate for studying mitochondrial membrane structure, function, and the electron transport chain.
• Diagnostic Reagent Production: Essential antigen in immunoassays (e.g., ELISA) for the detection of anti-cardiolipin antibodies, crucial in diagnosing antiphospholipid syndrome (APS).
• Pharmaceutical Development: Used in formulation studies for drug delivery systems and as a target in drug discovery programs for metabolic diseases.
• Liposome & Model Membrane Preparation: Incorporated into liposomes and bilayer systems to mimic inner mitochondrial membranes for permeability and fusion studies.
• Enzyme Activity Assays: Serves as a specific substrate for phospholipase assays and other lipid-metabolizing enzymes.
• Quality Control Standards: Acts as a reference standard in the quality control of diagnostic kits and related biological products.

Basic Information

Product Name	Cardiolipin (E. Coli) (Sodium Salt)
CAS No.	796964-05-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,3-Bis(sn-3'-phosphatidyl)-sn-glycerol (Sodium Salt); Diphosphatidylglycerol (E. Coli, Sodium Salt); Bis(1,2-diacyl-sn-glycero-3-phospho)-1,3-glycerol (Sodium Salt); CL (Na Salt); Cardiolipin Sodium Salt from E. coli; E. coli Cardiolipin (Sodium Salt); Bacterial Cardiolipin (Na+); Tetralinoleoylcardiolipin (Sodium Salt, from E. coli)
EINECS	Contact for details

Quality Control

Our Cardiolipin (E. Coli) (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, TLC for identity and lipid profile, and MS for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (TLC)	Conforms to standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures
Loss on Drying	≤ 5.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets research-grade requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.