Description

1H-Isoindole-1,3(2H)-Dione, 2-[3-[4-(2-Hydroxyethyl)-1-Piperazinyl]-3-Oxopropyl]- is a specialized heterocyclic organic compound featuring a phthalimide core linked to a hydroxyethylpiperazine moiety via a propionamide spacer. This molecular architecture makes it a valuable high-purity intermediate for advanced pharmaceutical synthesis and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science sectors for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or oncological pathways.
• Bioconjugation Reagent: Potential use in linking drug molecules to targeting ligands, antibodies, or polymers due to its reactive imide and hydroxyl groups.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polyimides or functional polymers with enhanced thermal and mechanical properties.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition or protein-ligand interactions.
• Material Science: Precursor for advanced organic materials, including liquid crystals or organic semiconductors.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 2-[3-[4-(2-Hydroxyethyl)-1-Piperazinyl]-3-Oxopropyl]-
CAS No.	796888-73-8
Molecular Formula	C17H21N3O4
Molecular Weight	331.37 g/mol
Synonyms	2-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]-3-oxopropyl]isoindoline-1,3-dione; N-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]-3-oxopropyl]phthalimide; 2-(3-Oxo-3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)isoindoline-1,3-dione; Phthalimide-PEG2-Hydroxyethyl Piperazine; Hydroxyethylpiperazine Phthalimide Propionamide; HPEPP; CAS 796888-73-8
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) with full traceability are provided. We support cGMP and ISO 9001 compliant production upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.