Description

1-(4-Trifluoromethyl-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, functionalized piperazine derivative designed for advanced chemical synthesis. This compound serves as a critical sulfonamide-based building block, offering a trifluoromethyl phenyl group that is highly valuable for modulating the physicochemical properties of target molecules. It is primarily utilized by pharmaceutical R&D and agrochemical research teams in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor for creating advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Research: Employed in academic and industrial laboratories for exploring new sulfonamide chemistry and constructing complex molecular architectures.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with tailored surface properties.

Basic Information

Product Name	1-(4-Trifluoromethyl-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	793679-07-9
Molecular Formula	C11H12ClF3N2O2S
Molecular Weight	328.74 g/mol
Synonyms	1-[(4-Trifluoromethyl)phenyl]sulfonylpiperazine hydrochloride; 4-(Trifluoromethyl)benzenesulfonylpiperazine hydrochloride; Piperazine, 1-[(4-(trifluoromethyl)phenyl)sulfonyl]-, hydrochloride; 1-(4-(Trifluoromethyl)phenylsulfonyl)piperazine HCl; 793679-07-9; 4-Trifluoromethylbenzenesulfonylpiperazine HCl; α,α,α-Trifluoro-p-toluenesulfonylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethyl-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.