Description

4-(5-(Trifluoromethyl)-2-Pyridyl)Piperazinecarbaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethylpyridine-piperazine scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with enhanced metabolic stability and membrane permeability. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly in therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to improve drug-like properties.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new generation pesticides and herbicides.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Utilized to develop molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	4-(5-(Trifluoromethyl)-2-Pyridyl)Piperazinecarbaldehyde
CAS No.	792940-10-4
Molecular Formula	C11H12F3N3O
Molecular Weight	259.23 g/mol
Synonyms	4-[5-(Trifluoromethyl)pyridin-2-yl]piperazine-1-carbaldehyde; 1-Formyl-4-[5-(trifluoromethyl)-2-pyridyl]piperazine; 4-(5-(Trifluoromethyl)-2-pyridinyl)-1-piperazinecarboxaldehyde; 4-(5-Trifluoromethylpyridin-2-yl)piperazine-1-carbaldehyde; 2-(1-Formylpiperazin-4-yl)-5-(trifluoromethyl)pyridine; 4-(5-(Trifluoromethyl)pyridin-2-yl)piperazine-1-carbaldehyde; Piperazinecarboxaldehyde, 4-[5-(trifluoromethyl)-2-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 4-(5-(Trifluoromethyl)-2-Pyridyl)Piperazinecarbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.