Description

D-Ribo-Hex-1-Enitol, 1,6-Anhydro-2-Deoxy-3,4-o-(1-Methylethylidene)-, Acetate (9Ci) is a sophisticated carbohydrate derivative and protected sugar intermediate of significant interest in advanced organic synthesis. This compound is valued for its unique stereochemistry and functional groups, which make it a versatile chiral building block for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other bioactive molecules where precise sugar moiety manipulation is critical.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery programs.
• Organic Synthesis Building Block: Used as a protected sugar derivative for the construction of complex carbohydrates, glycoconjugates, and natural products.
• Glycochemistry Research: Serves as a critical substrate in methodological studies for glycosylation reactions and carbohydrate chemistry.
• Bioconjugate Development: Employed in the design and synthesis of carbohydrate-based probes, ligands, and vaccine components.
• Process Chemistry: Utilized in route scouting and scale-up for the production of active pharmaceutical ingredients (APIs) requiring specific sugar scaffolds.

Basic Information

Product Name	D-Ribo-Hex-1-Enitol, 1,6-Anhydro-2-Deoxy-3,4-o-(1-Methylethylidene)-, Acetate (9Ci)
CAS No.	792935-78-5
Molecular Formula	C11H16O5
Molecular Weight	228.24 g/mol
Synonyms	1,6-Anhydro-2-deoxy-3,4-O-isopropylidene-D-ribo-hex-1-enitol Acetate; 3,4-O-Isopropylidene-1,6-anhydro-2-deoxy-D-ribo-hex-1-enitol Acetate; 1,6-Anhydro-2-deoxy-3,4-O-(1-methylethylidene)-D-ribo-hex-1-enitol Acetate; Protected D-Ribohexenitol Acetate; Carbohydrate Derivative CAS 792935-78-5.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Each batch of D-Ribo-Hex-1-Enitol derivative is characterized and tested to ensure identity, purity, and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profile is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.