Description

4-({4-[(4-Methyl-1-Piperazinyl)Sulfonyl]Phenyl}Amino)-4-Oxo-2-Butenoic Acid is a high-purity, non-natural amino acid derivative featuring a sulfonamide-linked piperazine moiety, making it a valuable synthetic intermediate for advanced research and development. Its molecular architecture is specifically designed to serve as a key building block in the creation of novel bioactive compounds, offering researchers a versatile handle for structure-activity relationship (SAR) studies. This compound is primarily targeted at the pharmaceutical, agrochemical, and advanced materials sectors, where it is utilized in medicinal chemistry for drug discovery, particularly in the development of enzyme inhibitors and targeted therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting kinase or protease enzymes.
• Medicinal Chemistry Research: Used as a scaffold or building block for Structure-Activity Relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Bioconjugation & Probe Development: The reactive butenoic acid group allows for conjugation to biomolecules (proteins, peptides) or fluorescent tags for biochemical assays.
• Agrochemical Synthesis: Employed in the research and development of novel active ingredients for crop protection products.
• Chemical Biology Tool: Utilized to create chemical probes for investigating biological pathways and protein function.
• Advanced Materials Precursor: Can be incorporated into specialty polymers or coatings to impart specific functional properties.

Basic Information

Product Name	4-({4-[(4-Methyl-1-Piperazinyl)Sulfonyl]Phenyl}Amino)-4-Oxo-2-Butenoic Acid
CAS No.	791790-43-7
Molecular Formula	C15H19N3O5S
Molecular Weight	353.40 g/mol
Synonyms	4-({4-[(4-Methylpiperazin-1-yl)sulfonyl]phenyl}amino)-4-oxobut-2-enoic acid; (2E)-4-({4-[(4-Methyl-1-piperazinyl)sulfonyl]phenyl}amino)-4-oxo-2-butenoic acid; 4-Oxo-4-({4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}amino)-2-butenoic Acid; 791790-43-7; 4-(4-(4-Methylpiperazine-1-sulfonyl)phenylamino)-4-oxobut-2-enoic acid; N-[4-[(4-Methyl-1-piperazinyl)sulfonyl]phenyl]-4-oxo-2-butenamide-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-({4-[(4-Methyl-1-Piperazinyl)Sulfonyl]Phenyl}Amino)-4-Oxo-2-Butenoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications aligned with industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) documenting purity (HPLC), identity (IR, NMR), and impurity profiles is provided with each shipment to guarantee traceability and support your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.