Description

Pyrazino[1,2-A]Indole, 8-Fluoro-1,2,3,4,10,10A-Hexahydro-4,6-Dimethyl-, (4R,10As)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of central nervous system (CNS) and oncology drug discovery. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Development: Serves as a critical starting material for producing compounds for pharmacological and toxicological evaluation.
• Process Chemistry: Employed in route scouting and scale-up development for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services.

Basic Information

Product Name	Pyrazino[1,2-A]Indole, 8-Fluoro-1,2,3,4,10,10A-Hexahydro-4,6-Dimethyl-, (4R,10As)- (9Ci)
CAS No.	791774-66-8
Molecular Formula	C15H17FN2
Molecular Weight	244.31 g/mol
Synonyms	(4R,10aS)-8-Fluoro-4,6-dimethyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole; 8-Fluoro-4,6-dimethyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole, (4R,10aS)-; (4R,10aS)-8-Fluoro-4,6-dimethyl-2,3,4,10-tetrahydropyrazino[1,2-a]indole; Pyrazino[1,2-a]indole, 8-fluoro-1,2,3,4,10,10a-hexahydro-4,6-dimethyl-, (4R,10aS)-; 791774-66-8; (4R,10aS)-8-Fluoro-4,6-dimethyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indole
EINECS	Contact for details

Quality Control

Our production of Pyrazino[1,2-A]Indole, 8-Fluoro-1,2,3,4,10,10A-Hexahydro-4,6-Dimethyl-, (4R,10As)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.