Description

1-(Tetrahydro-Pyran-4-Yl)-Piperazine Dihydrochloride is a high-purity, versatile pharmaceutical intermediate and building block of significant importance in modern organic synthesis. This compound matters for its crucial role as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. Pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) need this material for its reliable performance in complex synthetic pathways, enabling the creation of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for neurological and psychiatric drug discovery.
• Chemical Synthesis Reagent: Used in complex organic reactions, including amide coupling, reductive amination, and as a precursor for more elaborate heterocyclic systems.
• Ligand and Catalyst Development: Serves as a structural component in the design of novel ligands for metal catalysis and organocatalysts.
• Agrochemical Research: Employed as an intermediate in the research and development of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or additive in the synthesis of specialized polymers and advanced materials.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry programs and process chemistry optimization in both university and industrial laboratory settings.

Basic Information

Product Name	1-(Tetrahydro-Pyran-4-Yl)-Piperazine Dihydrochloride
CAS No.	790223-65-3
Molecular Formula	C9H20Cl2N2O
Molecular Weight	243.17 g/mol
Synonyms	1-(Oxan-4-yl)piperazine dihydrochloride; 1-(Tetrahydropyran-4-yl)piperazine dihydrochloride; 4-(Piperazin-1-yl)tetrahydro-2H-pyran dihydrochloride; Piperazine, 1-(tetrahydro-4H-pyran-4-yl)-, dihydrochloride; THP-Piperazine Dihydrochloride; 790223-65-3; 1-(Tetrahydro-2H-pyran-4-yl)piperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Tetrahydro-Pyran-4-Yl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.