Description

1-(4-Trifluoromethoxy-Phenyl)-Piperazin-2-One is a high-purity, advanced pharmaceutical intermediate with a distinct trifluoromethoxy-phenylpiperazinone structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric drug research. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers engaged in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging the bioactivity of the trifluoromethoxy and piperazinone motifs.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific pharmacophore.
• Material Science Applications: Potential use in the development of specialty polymers and advanced functional materials.

Basic Information

Product Name	1-(4-Trifluoromethoxy-Phenyl)-Piperazin-2-One
CAS No.	790195-84-5
Molecular Formula	C11H11F3N2O2
Molecular Weight	260.21 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]piperazin-2-one; 1-(4-Trifluoromethoxyphenyl)-2-piperazinone; 4-Trifluoromethoxyphenylpiperazinone; 790195-84-5; 1-(4-(Trifluoromethoxy)phenyl)piperazin-2-one; 2-Piperazinone, 1-[4-(trifluoromethoxy)phenyl]-; TFMPP derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethoxy-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.