Description

(4-Boc-Piperazin-1-Yl)-Oxo-Acetic Acid CAS NO 788153-44-6 is a high-purity, protected piperazine derivative widely used as a key synthetic intermediate in pharmaceutical research and development. Its primary value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Protease Inhibitor Synthesis: Used in the construction of complex molecules designed to inhibit specific enzymes.
• Peptidomimetic Chemistry: Serves as a core component for creating peptide-like compounds with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the development of tool compounds for target identification and validation in biological systems.
• Library Synthesis for Drug Discovery: A valuable reagent for generating diverse compound libraries via parallel and combinatorial chemistry.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic routes for potential APIs.

Basic Information

Product Name	(4-Boc-Piperazin-1-Yl)-Oxo-Acetic Acid
CAS No.	788153-44-6
Molecular Formula	C11H18N2O5
Molecular Weight	258.27 g/mol
Synonyms	2-[(4-{[(tert-Butoxy)carbonyl]amino}piperazin-1-yl]-2-oxoacetic Acid; 2-(4-Boc-piperazin-1-yl)-2-oxoacetic Acid; 2-Oxo-2-(4-{[(2-methylpropan-2-yl)oxy]carbonyl}piperazin-1-yl)acetic Acid; N-Boc-piperazinylglyoxylic Acid; (4-Boc-1-piperazinyl)oxoacetic Acid; 1-Boc-4-(oxalyl)piperazine; tert-Butyl 4-(oxalyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (4-Boc-Piperazin-1-Yl)-Oxo-Acetic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and development use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.