Description

2-Piperazinecarboxylicacid,5-(1-Methylethyl)-,(2R-Cis)-(9Ci) is a high-purity chiral piperazine derivative, a critical building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an invaluable intermediate for creating complex molecules with specific biological activity. This compound is primarily required by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective synthesis to construct enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with improved efficacy and selectivity.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and peptide mimetics for biochemical studies.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialized polymers and advanced materials.

Basic Information

Product Name	2-Piperazinecarboxylicacid,5-(1-Methylethyl)-,(2R-Cis)-(9Ci)
CAS No.	782424-04-8
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	(2R,5S)-5-Isopropylpiperazine-2-carboxylic acid; (2R,5S)-2-Piperazinecarboxylic acid, 5-(1-methylethyl)-; cis-5-Isopropyl-D-piperazine-2-carboxylic acid; (2R-cis)-5-(1-Methylethyl)-2-piperazinecarboxylic acid; 5-Isopropyl-D-proline piperazine isomer; D-cis-5-Isopropylpiperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylicacid,5-(1-Methylethyl)-,(2R-Cis)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), enantiomeric excess, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.