Description

2H-Pyrido[1,2-A]Pyrazine-6-Methanol,Octahydro-,(6R,9Ar)-Rel-(9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for the research and development of novel pharmaceutical agents, particularly in the areas of central nervous system (CNS) and metabolic disorder therapeutics. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Process Chemistry Development: Utilized in the scale-up and route scouting for the commercial production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Acts as a core structure for developing tool compounds to study biological pathways and protein functions.
• Academic Research: Used in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-6-Methanol,Octahydro-,(6R,9Ar)-Rel-(9Ci)
CAS No.	781640-33-3
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	(6R,9aR)-Octahydro-2H-pyrido[1,2-a]pyrazine-6-methanol; rel-(6R,9aR)-Octahydro-2H-pyrido[1,2-a]pyrazine-6-methanol; (6R,9aR)-Octahydro-2H-pyrido[1,2-a]pyrazin-6-ylmethanol; 2H-Pyrido[1,2-a]pyrazine-6-methanol, octahydro-, (6R,9aR)-rel-; (6R,9aR)-rel-Octahydro-2H-pyrido[1,2-a]pyrazine-6-methanol; 781640-33-3; SCHEMBL21801027; A1-00826
EINECS	Contact for details

Quality Control

Our 2H-Pyrido[1,2-A]Pyrazine-6-Methanol,Octahydro-,(6R,9Ar)-Rel-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.