Description

2-(Trifluoromethyl)-5,6,7,8-Tetrahydro-8-Methyl-[1,2,4]Triazolo[1,5-A]Pyrazine is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyrazine heterocyclic core and a strategically positioned trifluoromethyl group. This compound is of significant value for medicinal chemistry research and development, offering a versatile scaffold for creating novel bioactive molecules. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and crop protection agents.

Application

• Key building block in the research and development of novel active pharmaceutical ingredients (APIs).
• Advanced intermediate for synthesizing potential therapeutic agents targeting central nervous system (CNS) disorders.
• Precursor in the discovery of agrochemicals, including herbicides and insecticides.
• Versatile scaffold for structure-activity relationship (SAR) studies in medicinal chemistry.
• Used in the synthesis of compounds for preclinical and clinical research studies.
• Intermediate in the development of fluorinated compounds for enhanced metabolic stability and bioavailability.

Basic Information

Product Name	2-(Trifluoromethyl)-5,6,7,8-Tetrahydro-8-Methyl-[1,2,4]Triazolo[1,5-A]Pyrazine
CAS No.	781614-02-6
Molecular Formula	C8H11F3N4
Molecular Weight	220.20 g/mol
Synonyms	8-Methyl-2-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine; 2-(Trifluoromethyl)-8-methyl-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 781614-02-6; Triazolopyrazine derivative; CF3-Triazolopyrazine intermediate
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-5,6,7,8-Tetrahydro-8-Methyl-[1,2,4]Triazolo[1,5-A]Pyrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.