Description

2-Piperazinecarboxaldehyde,1,4-Dimethyl-3,6-Dioxo-,Ion(1-)(9Ci) is a specialized heterocyclic building block with a unique piperazine-dione core functionalized with an aldehyde group. This compound matters as a versatile and high-value synthetic intermediate, enabling the construction of complex molecular architectures in advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in the development of protease inhibitors and other biologically relevant small molecules. Its distinct ionic character and reactive aldehyde moiety make it a critical reagent for targeted chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in protease inhibitor and neurological disorder research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation, protein labeling, and the development of activity-based probes.
• Organic Synthesis: A versatile precursor for constructing complex piperazine and diketopiperazine derivatives via condensation and cyclization reactions.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Piperazinecarboxaldehyde,1,4-Dimethyl-3,6-Dioxo-,Ion(1-)(9Ci)
CAS No.	781563-71-1
Molecular Formula	C7H10N2O3-
Molecular Weight	170.17 g/mol
Synonyms	1,4-Dimethyl-3,6-dioxopiperazine-2-carboxaldehyde anion; 1,4-Dimethyl-2,5-diketopiperazine-2-carboxaldehyde; 2-Formyl-1,4-dimethyl-3,6-dioxopiperazin-1-ium; 2-Carbaldehyde-1,4-dimethyl-3,6-piperazinedione; 1,4-Dimethyl-3,6-dioxo-2-piperazinecarboxaldehyde ion(1-); (1,4-Dimethyl-3,6-dioxopiperazin-2-yl)methanolate (tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxaldehyde,1,4-Dimethyl-3,6-Dioxo-,Ion(1-)(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided. Keep the container sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.