Description

Pyrazine, 5-Bromo-1,2-Dihydro- (9Ci) is a halogenated dihydropyrazine derivative, a versatile and valuable synthetic building block in advanced organic chemistry. Its core value lies in its functionalized pyrazine ring, which serves as a key precursor for the development of complex heterocyclic compounds, particularly in pharmaceutical research. This intermediate is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and material science industries who require high-purity, specialized raw materials for synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced organic electronic materials, such as conductive polymers or light-emitting compounds.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A key reagent for synthetic methodology development and exploratory research in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Pyrazine, 5-Bromo-1,2-Dihydro- (9Ci)
CAS No.	780811-45-2
Molecular Formula	C4H5BrN2
Molecular Weight	161.00 g/mol
Synonyms	5-Bromo-1,2-dihydropyrazine; 5-Bromo-1,2-dihydro-pyrazine; 1,2-Dihydro-5-bromopyrazine; 5-Bromopyrazine, 1,2-dihydro-; 5-Bromo-3,4-dihydropyrazine; 5-Bromo-1,2-dihydropyrazine (9CI); 5-Bromo-1,2-dihydropyrazine (9Ci)
EINECS	Contact for details

Quality Control

Our Pyrazine, 5-Bromo-1,2-Dihydro- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.