Description

3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-5,8-Dimethyl-[1,2,4]Triazolo[4,3-A]Pyrazine is a high-value, heterocyclic organic compound featuring a fused triazolopyrazine core with a strategically positioned trifluoromethyl group. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization due to its privileged heterocyclic structure.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the triazole and pyrazine motifs.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study enzyme function or biological pathways.
• Material Science Research: Potential precursor for specialty chemicals or functional materials, exploring the properties imparted by the fluorine atoms.

Basic Information

Product Name	3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-5,8-Dimethyl-[1,2,4]Triazolo[4,3-A]Pyrazine
CAS No.	780754-27-0
Molecular Formula	C9H11F3N4
Molecular Weight	232.21 g/mol
Synonyms	5,8-Dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 3-(Trifluoromethyl)-5,8-dimethyl-4,5,6,7-tetrahydro-1H-[1,2,4]triazolo[4,3-a]pyrazine; 5,8-Dimethyl-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-[1,2,4]triazolo[4,3-a]pyrazine; [1,2,4]Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-5,8-dimethyl-3-(trifluoromethyl)-; CAS 780754-27-0
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-5,8-Dimethyl-[1,2,4]Triazolo[4,3-A]Pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support your regulatory and R&D needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard grade meets typical requirements for advanced pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.