Description

1-(4-Fluoro-Phenyl)-Piperazin-2-One is a high-purity fluorinated piperazinone derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in enabling the development of novel bioactive molecules, particularly for the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers in medicinal chemistry, process R&D, and fine chemical production who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) due to its fluorinated aromatic and heterocyclic structure.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides, leveraging the stability imparted by the fluorine atom.
• Fine Chemical Manufacturing: Serves as a precursor for other specialty chemicals and complex organic molecules in custom synthesis projects.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme inhibition or receptor binding assays.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-Piperazin-2-One
CAS No.	780753-89-1
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	1-(4-Fluorophenyl)piperazin-2-one; 4-Fluorophenylpiperazinone; 1-(p-Fluorophenyl)-2-piperazinone; 2-Piperazinone, 1-(4-fluorophenyl)-; 780753-89-1; 1-(4-FLUORO-PHENYL)-PIPERAZIN-2-ONE; 1-(4-Fluorophenyl)piperazin-2-one (9CI)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-Piperazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.