Description

1-(2-Methylbenzoyl)Piperazine is a specialized organic compound belonging to the class of N-acylpiperazines, serving as a crucial building block in advanced chemical synthesis. This high-purity intermediate is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex piperazine-based scaffolds and amide bond formations.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and pesticide development.
• Material Science Precursor: Acts as a monomer or modifying agent in the development of specialty polymers and advanced materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Methylbenzoyl)Piperazine
CAS No.	775579-10-7
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	1-(2-Methylbenzoyl)piperazine; 2-Methyl-N-(piperazin-1-yl)benzamide; o-Toluoylpiperazine; 1-(o-Toluoyl)piperazine; Piperazine, 1-(2-methylbenzoyl)-; N-(2-Methylbenzoyl)piperazine; Benzamide, 2-methyl-N-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 1-(2-Methylbenzoyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.