Description

1-Piperazinecarboxylic Acid, 4-[[1-[(1,1-Dimethylethoxy)Carbonyl]-4-Piperidinyl]Methyl]-, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex, multi-ring structure. This compound is critical for research and development in medicinal chemistry, particularly for constructing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for preclinical and clinical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Protease Inhibitor Research: Used in the development of protease inhibitors, where its piperazine and piperidine motifs are valuable for molecular recognition.
• Peptidomimetic Chemistry: Acts as a scaffold for creating peptidomimetics, which are molecules that mimic peptides but with improved stability and bioavailability.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-[[1-[(1,1-Dimethylethoxy)Carbonyl]-4-Piperidinyl]Methyl]-, Phenylmethyl Ester
CAS No.	775288-80-7
Molecular Formula	C24H36N2O4
Molecular Weight	416.56 g/mol
Synonyms	4-[(1-{[(Tert-Butoxy)Carbonyl]Piperidin-4-Yl}Methyl)Piperazine-1-Carboxylic Acid Benzyl Ester; Benzyl 4-((1-(Tert-Butoxycarbonyl)Piperidin-4-Yl)Methyl)Piperazine-1-Carboxylate; 1-Boc-4-(4-(Benzyloxycarbonyl)Piperazin-1-Ylmethyl)Piperidine; N-Boc-4-Piperidinemethyl-N-Carbobenzyloxypiperazine; (Benzyloxy)Carbonyl-4-((1-Boc-4-Piperidyl)Methyl)Piperazine; 4-((1-Boc-Piperidin-4-Yl)Methyl)Piperazine-1-Carboxylic Acid Benzyl Ester; 1-N-Boc-4-N-Cbz-Aminomethyl-Piperidine
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylic Acid, 4-[[1-[(1,1-Dimethylethoxy)Carbonyl]-4-Piperidinyl]Methyl]-, Phenylmethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.