Description

Ethyl 2-(3-Oxopiperazin-1-Yl)Acetate is a high-purity pharmaceutical intermediate featuring a piperazinone core, a privileged scaffold in medicinal chemistry. This compound is valued for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in drug discovery and development pipelines. It is primarily sought by research institutions and pharmaceutical companies engaged in the creation of new therapeutic agents, including potential kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Building Block: Used for constructing complex heterocyclic compounds and exploring structure-activity relationships (SAR) in drug discovery programs.
• Kinase Inhibitor Synthesis: Serves as a core fragment in the design and synthesis of potential kinase inhibitor candidates for oncology and other therapeutic areas.
• Chemical Research: Employed in academic and industrial R&D for methodological studies and the synthesis of novel chemical entities.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	Ethyl 2-(3-Oxopiperazin-1-Yl)Acetate
CAS No.	774493-57-1
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	1-Piperazineacetic acid, 3-oxo-, ethyl ester; Ethyl (3-oxopiperazin-1-yl)acetate; 2-(3-Oxopiperazin-1-yl)acetic acid ethyl ester; 1-(Ethoxycarbonylmethyl)-3-oxopiperazine; 3-Oxo-1-piperazineacetic acid ethyl ester; Ethyl 2-(3-oxo-1-piperazinyl)acetate; 774493-57-1
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Oxopiperazin-1-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediates and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.