Description

Piperazine, 1-[(2R)-3-Fluoro-2-Methylpropyl]- (9Ci) is a specialized chiral piperazine derivative, a high-value intermediate in modern synthetic chemistry. Its core value lies in its unique molecular architecture, featuring a fluorinated alkyl side chain, which is critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fine Chemical Production: An intermediate for the manufacture of other high-purity, complex fluorinated organic compounds.

Basic Information

Product Name	Piperazine, 1-[(2R)-3-Fluoro-2-Methylpropyl]- (9Ci)
CAS No.	774173-62-5
Molecular Formula	C8H17FN2
Molecular Weight	160.24 g/mol
Synonyms	1-[(2R)-3-Fluoro-2-methylpropyl]piperazine; (R)-1-(3-Fluoro-2-methylpropyl)piperazine; (R)-3-Fluoro-2-methylpropyl-piperazine; 774173-62-5; UNII-9Q2K8Q7G4F; Piperazine, 1-[(2R)-3-fluoro-2-methylpropyl]-; SCHEMBL23342277; DTXSID90648669
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 1-[(2R)-3-Fluoro-2-Methylpropyl]- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, NMR, and MS, to ensure high chemical and enantiomeric purity, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.