Description

2-o-Tolylpiperazine is a versatile organic building block and intermediate of significant interest in advanced chemical synthesis. Its piperazine core linked to an o-tolyl group makes it a valuable scaffold for constructing more complex molecules, particularly in pharmaceutical research and development. This compound is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides, leveraging its heterocyclic structure.
• Ligand Synthesis: Acts as a building block for creating specialized ligands used in catalysis and metal complexation studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-o-Tolylpiperazine
CAS No.	774157-36-7
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	2-(2-Methylphenyl)piperazine; 1-(2-Methylphenyl)piperazine; o-Tolylpiperazine; 2-Methylphenylpiperazine; 2-(o-Tolyl)piperazine; 1-(o-Tolyl)piperazine; Piperazine, 1-(2-methylphenyl)-; 2-(2-Tolyl)piperazine
EINECS	Contact for details

Quality Control

Our 2-o-Tolylpiperazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.