Description

Piperazine, 2,5-Bis(Fluoromethyl)-, cis- (9Ci) is a specialized fluorinated piperazine derivative with the CAS number 774148-59-3. This compound is a high-value building block prized for its unique cis-configuration and the reactivity imparted by its fluoromethyl groups, enabling precise molecular modifications. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential compound for studying structure-activity relationships (SAR) and introducing fluorine into complex molecular architectures.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Item	Detail
Product Name	Piperazine, 2,5-Bis(Fluoromethyl)-, cis- (9Ci)
CAS No.	774148-59-3
Molecular Formula	C8H14F2N2
Molecular Weight	176.21 g/mol
Synonyms	cis-2,5-Bis(fluoromethyl)piperazine; 2,5-Bis(fluoromethyl)piperazine (cis-); cis-1,4-Bis(fluoromethyl)piperazine; 1,4-Bis(fluoromethyl)piperazine, cis-; Piperazine, 2,5-bis(fluoromethyl)-, (2R,5S)-rel-; (2R,5S)-rel-2,5-Bis(fluoromethyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2,5-Bis(Fluoromethyl)-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.