Description

1-[(1R)-Phenylethyl]Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and ligand for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and specialty chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring high stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Catalyst Ligand: Used as a chiral ligand in asymmetric catalysis for the production of high-value, optically active compounds.
• Agrochemical Research: Employed in the development of novel, stereoselective pesticides and herbicides.
• Fine Chemical Synthesis: A versatile building block for creating complex molecules in custom synthesis and process development.
• Academic & R&D: Serves as a reference standard and starting material in university and corporate research laboratories for methodological studies.

Basic Information

Product Name	1-[(1R)-Phenylethyl]Piperazine
CAS No.	773848-51-4
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	(R)-1-Phenylethylpiperazine; (R)-1-(1-Phenylethyl)piperazine; (R)-N-(1-Phenylethyl)piperazine; (1R)-1-Phenylethylpiperazine; (R)-(-)-1-(1-Phenylethyl)piperazine; 1-[(R)-Phenylethyl]piperazine; (R)-1-(α-Methylbenzyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[(1R)-Phenylethyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.