Description

Piperazine, 1-Methyl-4-(3-Pyrrolidinyl)-, (R)- (9Ci) is a high-purity, chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and oncology. Pharmaceutical research and development organizations require this specific stereoisomer to ensure the efficacy and safety of their final drug candidates, making reliable access to a high-quality source essential for their projects.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• Neurological Drug Research: Used in the development of ligands and modulators for central nervous system (CNS) receptors.
• Oncological Therapeutics: Serves as a structural component in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Agrochemical Research: Utilized in the discovery of new, selective pesticides and herbicides that require specific stereochemistry for activity.
• Chemical Biology & Proteomics: Acts as a scaffold or linker in the design of molecular probes for studying enzyme function and protein-protein interactions.

Basic Information

Product Name	Piperazine, 1-Methyl-4-(3-Pyrrolidinyl)-, (R)- (9Ci)
CAS No.	771438-38-1
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	(R)-1-Methyl-4-(pyrrolidin-3-yl)piperazine; (R)-1-Methyl-4-(3-pyrrolidinyl)piperazine; (3R)-1-Methyl-4-(3-pyrrolidinyl)piperazine; 1-Methyl-4-[(3R)-pyrrolidin-3-yl]piperazine; (R)-N-Methyl-4-(3-pyrrolidinyl)piperazine; (R)-3-(4-Methylpiperazin-1-yl)pyrrolidine; UNII-2Q8K7F3Q8R
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Methyl-4-(3-Pyrrolidinyl)-, (R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.