Description

2H-Imidazo[4,5-B]Pyrazin-2-One, 6-(1,3-Benzodioxol-5-Yl)-1,3-Dihydro-1-[(1S)-1-Phenylethyl]- is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical synthetic intermediate for the creation of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting specific enzyme pathways.
• Kinase Inhibitor Research: Used in the development and study of novel kinase inhibitors for cancer therapy applications.
• Chemical Biology Probes: Serves as a core structure for creating probes to study protein function and cellular signaling mechanisms.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its (S)-configured phenylethyl group, enabling the production of enantiomerically pure compounds.
• Medicinal Chemistry Optimization: Provides a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2H-Imidazo[4,5-B]Pyrazin-2-One, 6-(1,3-Benzodioxol-5-Yl)-1,3-Dihydro-1-[(1S)-1-Phenylethyl]-
CAS No.	767343-27-1
Molecular Formula	C20H16N4O3
Molecular Weight	360.37 g/mol
Synonyms	1-[(1S)-1-Phenylethyl]-6-(1,3-benzodioxol-5-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one; (S)-1-Phenylethyl-6-(benzo[d][1,3]dioxol-5-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one; 767343-27-1; UNII-7K3S4A5F74; 7K3S4A5F74; CHEMBL3185142; SCHEMBL15450497; DTXSID60646369
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, potency, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support compliance with ICH guidelines for impurities and stability, making this product suitable for use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.