Description

6-Bromo-N2-(Cyclopropylmethyl)Pyrazine-2,3-Diamine is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyrazine-diamine core functionalized with a cyclopropylmethyl group. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the design and creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.

Basic Information

Product Name	6-Bromo-N2-(Cyclopropylmethyl)Pyrazine-2,3-Diamine
CAS No.	767343-19-1
Molecular Formula	C8H11BrN4
Molecular Weight	243.11 g/mol
Synonyms	6-Bromo-N2-(cyclopropylmethyl)pyrazine-2,3-diamine; 2,3-Pyrazinediamine, 6-bromo-N2-(cyclopropylmethyl)-; 6-Bromo-2-(cyclopropylmethylamino)pyrazin-3-amine; 6-Bromo-3-amino-2-(cyclopropylmethylamino)pyrazine; 767343-19-1; 6-Br-CPMPDA; N2-Cyclopropylmethyl-6-bromopyrazine-2,3-diamine
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-N2-(Cyclopropylmethyl)Pyrazine-2,3-Diamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. Each lot is subjected to comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.