Description

cis-3-Methoxy-4-Aminopiperidine is a high-purity, functionalized piperidine derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in the strategic positioning of its methoxy and amino groups, which enable precise molecular modifications for creating complex, bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Ligand and Catalyst Development: Useful for constructing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	cis-3-Methoxy-4-Aminopiperidine
CAS No.	766556-99-4
Molecular Formula	C6H14N2O
Molecular Weight	130.19 g/mol
Synonyms	4-Amino-3-methoxypiperidine (cis-); (3R,4S)-3-Methoxy-4-aminopiperidine; (3S,4R)-3-Methoxy-4-aminopiperidine; cis-4-Amino-3-methoxypiperidine; 3-Methoxy-4-aminopiperidine, cis-; 1-Piperidinamine, 3-methoxy-, (3R,4S)-rel-; 766556-99-4; 3-Methoxy-piperidin-4-ylamine
EINECS	Contact for details

Quality Control

Our cis-3-Methoxy-4-Aminopiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), chiral excess, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.