Description

5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Monohydrochloride is a high-purity, synthetically derived chemical intermediate of significant importance in modern pharmaceutical research and development. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly those targeting central nervous system and other therapeutic areas. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic candidates.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the development and optimization of scalable synthetic routes for potential drug candidates.
• Reference Standard: Can be utilized as an analytical reference standard for quality control and method development in API manufacturing.
• Biochemical Tool Compound: Employed in biochemical assays and pharmacological studies to investigate specific biological pathways and receptor interactions.
• Custom Synthesis: Acts as a starting material or intermediate for custom synthesis services, enabling the production of specialized derivatives and analogs.

Basic Information

Product Name	5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Monohydrochloride
CAS No.	765935-67-9
Molecular Formula	C15H19N2O3•HCl
Molecular Weight	308.79 g/mol (Free base: 275.33 g/mol)
Synonyms	5-(Piperazin-1-yl)-2-benzofurancarboxylic acid ethyl ester hydrochloride; Ethyl 5-(piperazin-1-yl)-1-benzofuran-2-carboxylate hydrochloride; 5-Piperazinylbenzofuran-2-carboxylic acid ethyl ester HCl; Ethyl 5-(1-piperazinyl)benzofuran-2-carboxylate monohydrochloride; 5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester HCl salt; CAS 765935-67-9
EINECS	Contact for details

Quality Control

Our 5-(1-Piperazinyl)-2-Benzofurancarboxylic Acid Ethyl Ester Monohydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.