Description

2H-Pyrido[1,2-A]Pyrazine-7-Methanol,Octahydro-,(7R,9As)-(9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, enabling precise molecular construction. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for creating complex molecules with specific biological activities, particularly in the areas of central nervous system (CNS) and metabolic disorder therapeutics. Its defined stereochemistry at the 7R and 9As positions is critical for ensuring the efficacy and safety profile of the final target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new catalytic systems for stereoselective transformations.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical space and optimize lead compounds for potency and selectivity.
• Fine Chemical Synthesis: Acts as a building block for the production of complex, high-value specialty chemicals used in agrochemicals and advanced materials.
• Academic & Industrial R&D: Utilized in research institutions and corporate R&D departments for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2H-Pyrido[1,2-A]Pyrazine-7-Methanol,Octahydro-,(7R,9As)-(9Ci)
CAS No.	764714-59-2
Molecular Formula	C9H16N2O
Molecular Weight	168.24 g/mol
Synonyms	(7R,9aS)-Octahydro-2H-pyrido[1,2-a]pyrazine-7-methanol; (7R,9aS)-Octahydro-2H-pyrido[1,2-a]pyrazin-7-ylmethanol; (7R,9aS)-2H-Pyrido[1,2-a]pyrazine-7-methanol, octahydro-; (7R,9aS)-Octahydro-2H-pyrido[1,2-a]pyrazine-7-carbinol; UNII-6V8Q8KQ5W5; 6V8Q8KQ5W5; SCHEMBL235454; BCP31033
EINECS	Contact for details

Quality Control

Our 2H-Pyrido[1,2-A]Pyrazine-7-Methanol,Octahydro-,(7R,9As)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We adhere to cGMP guidelines for the production of advanced intermediates, ensuring traceability, consistency, and regulatory compliance for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.