Description

2-(4-Boc-Piperazinyl)-2-(4-Bromo-Phenyl)Acetic Acid CAS NO 763109-75-7 is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine ring and a brominated phenylacetic acid core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors and other enzyme-targeting therapeutics.
• Ligand and Scaffold Development: Employed for creating complex molecular scaffolds and ligands for biological target screening.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and protein function.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(4-Bromo-Phenyl)Acetic Acid
CAS No.	763109-75-7
Molecular Formula	C₁₇H₂₃BrN₂O₄
Molecular Weight	399.28 g/mol
Synonyms	2-(4-Bromo-phenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; 2-(4-Bromo-phenyl)-2-(4-tert-butoxycarbonyl-piperazin-1-yl)-acetic acid; 2-(4-Boc-piperazin-1-yl)-2-(4-bromophenyl)acetic acid; N-Boc-4-(4-bromophenyl)(hydroxy)methylpiperazine; 763109-75-7; tert-Butyl 4-[(4-bromophenyl)(carboxymethyl)amino]piperidine-1-carboxylate (related isomer); Boc-4-Br-Phe-Pip-OH (abbreviation).
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(4-Bromo-Phenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.