Description

2-Methoxy-4-[4-(4-Methylpiperazin-1-Yl)Piperidin-1-Yl]Aniline is a high-purity, advanced pharmaceutical intermediate featuring a complex piperazine-piperidine-aniline scaffold. This compound is of significant commercial importance for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, where reliable supply and stringent quality are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for constructing novel chemical entities (NCEs) and structure-activity relationship (SAR) studies.
• Research & Development (R&D): Essential for academic and industrial R&D labs focusing on heterocyclic chemistry and new drug discovery pipelines.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical intermediate in the multi-step synthesis of final API compounds under controlled GMP environments.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs specializing in custom synthesis and scale-up of pharmaceutical intermediates.

Basic Information

Item	Detail
Product Name	2-Methoxy-4-[4-(4-Methylpiperazin-1-Yl)Piperidin-1-Yl]Aniline
CAS No.	761440-75-9
Molecular Formula	C17H28N4O
Molecular Weight	304.43 g/mol
Synonyms	1-(4-Amino-2-methoxyphenyl)-4-(4-methylpiperazin-1-yl)piperidine; 4-[4-(4-Methyl-1-piperazinyl)-1-piperidinyl]-2-methoxybenzenamine; 2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]aniline; 761440-75-9; 2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline; 4-[4-(4-Methylpiperazin-1-yl)piperidin-1-yl]-2-methoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-[4-(4-Methylpiperazin-1-Yl)Piperidin-1-Yl]Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.