Description

Ipragliflozin is a potent and selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, a key active pharmaceutical ingredient (API) in the treatment of type 2 diabetes mellitus. Its mechanism of action promotes the renal excretion of excess glucose, offering a distinct therapeutic pathway for glycemic control. This high-purity compound is essential for pharmaceutical manufacturers and research institutions developing innovative antidiabetic medications and conducting metabolic disease studies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of oral antidiabetic drugs for type 2 diabetes management.
• Research & Development: Critical for preclinical and clinical research into SGLT2 inhibition, pharmacokinetics, and new combination therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Metabolic Disorder Studies: Used in academic and institutional research to investigate mechanisms of glucose homeostasis and related metabolic pathways.
• Generic Drug Manufacturing: A vital component for companies producing bioequivalent versions of SGLT2 inhibitor medications.
• Formulation Development: Employed in the development of various dosage forms, including tablets and fixed-dose combinations.

Basic Information

Product Name	Ipragliflozin
CAS No.	761423-87-4
Molecular Formula	C21H21FO5S
Molecular Weight	404.45 g/mol
Synonyms	Ipragliflozin L-Proline; (1S)-1,5-Anhydro-1-C-[4-fluoro-3-[(4-methoxyphenyl)methyl]phenyl]-D-glucitol; ASP1941; Suglat® (Brand Name); (1S)-1,5-Anhydro-1-C-[3-[(4-methoxybenzyl)phenyl]-4-fluorophenyl]-D-glucitol; SGLT2 Inhibitor ASP1941
EINECS	Contact for details

Quality Control

Our Ipragliflozin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.5%
Chiral Purity	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.