Description

Piperazine, 1-(3-Mercapto-2-Methyl-1-Oxopropyl)-4-Methyl-, (S)- (9Ci) is a specialized chiral piperazine derivative featuring a mercaptopropanoyl side chain, making it a valuable building block in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly for creating novel active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical and biotechnology companies for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular diseases.
• Ligand Precursor: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexation studies.
• Peptidomimetic Research: Acts as a constrained scaffold in the design and synthesis of peptidomimetics and protease inhibitors.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	Piperazine, 1-(3-Mercapto-2-Methyl-1-Oxopropyl)-4-Methyl-, (S)- (9Ci)
CAS No.	761357-97-5
Molecular Formula	C9H18N2O2S
Molecular Weight	218.32 g/mol
Synonyms	(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-methylpiperazine; 4-Methyl-1-[(2S)-3-mercapto-2-methylpropanoyl]piperazine; L-3-Mercapto-2-methylpropionyl-4-methylpiperazine; (S)-4-Methyl-1-(3-mercapto-2-methylpropanoyl)piperazine; 1-[(2S)-3-Mercapto-2-methylpropanoyl]-4-methylpiperazine; (2S)-3-Mercapto-2-methyl-1-(4-methylpiperazin-1-yl)propan-1-one
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Mercapto-2-Methyl-1-Oxopropyl)-4-Methyl-, (S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.