Description

1-[(1S)-Phenylethyl]Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and stereochemically defined building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and psychiatric disorders.
• Asymmetric Catalyst Ligand: Used in the synthesis of chiral ligands for metal-catalyzed reactions to produce enantiomerically pure compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of novel, stereoselective pesticides and herbicides.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-[(1S)-Phenylethyl]Piperazine
CAS No.	759457-60-8
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	(S)-1-(1-Phenylethyl)piperazine; (S)-1-Phenylethylpiperazine; 1-[(1S)-1-Phenylethyl]piperazine; (S)-N-(1-Phenylethyl)piperazine; 1-[(S)-α-Methylbenzyl]piperazine; (S)-(-)-1-(1-Phenylethyl)piperazine; (S)-1-(α-Methylbenzyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[(1S)-Phenylethyl]Piperazine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC/MS, to verify identity, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.