Description

1-(2,4,6-Trifluorophenyl)Piperazine is a high-purity fluorinated piperazine derivative, a key building block in advanced organic synthesis. Its trifluoromethylphenyl moiety provides unique electronic and steric properties, making it invaluable for modulating the biological activity and physicochemical characteristics of target molecules. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Chemical Biology Probe Development: Employed to create labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	1-(2,4,6-Trifluorophenyl)Piperazine
CAS No.	759443-28-2
Molecular Formula	C10H10F3N2
Molecular Weight	218.20 g/mol
Synonyms	1-(2,4,6-Trifluorophenyl)piperazine; 2,4,6-Trifluoro-1-(1-piperazinyl)benzene; 2,4,6-Trifluorophenylpiperazine; Piperazine, 1-(2,4,6-trifluorophenyl)-; 759443-28-2; 1-(2,4,6-Trifluorophenyl)piperazine hydrochloride (salt form); TFP-Piperazine
EINECS	Contact for details

Quality Control

Every batch of 1-(2,4,6-Trifluorophenyl)Piperazine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.