Description

Piperazine, 2-Ethynyl-1-(1-Methylethyl)- (9Ci) is a specialized piperazine derivative featuring an ethynyl substituent, which serves as a versatile synthetic building block for advanced organic synthesis. This compound is valued for its unique molecular scaffold, enabling the construction of complex heterocyclic systems and pharmacologically active molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for lead compound optimization and novel chemical entity development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core.
• Chemical Synthesis Building Block: The ethynyl group provides a handle for click chemistry (e.g., Huisgen cycloaddition) and other coupling reactions to create diverse molecular libraries.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	Piperazine, 2-Ethynyl-1-(1-Methylethyl)- (9Ci)
CAS No.	759401-74-6
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	2-Ethynyl-1-isopropylpiperazine; 1-Isopropyl-2-ethynylpiperazine; 2-Ethynyl-1-(propan-2-yl)piperazine; 759401-74-6; 1-(1-Methylethyl)-2-ethynyl-piperazine; Piperazine, 1-(1-methylethyl)-2-ethynyl-; 2-Ethynyl-1-(1-methylethyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2-Ethynyl-1-(1-Methylethyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.