Description

Piperazine, 2,3,5-Trimethyl-, (2Alpha,3Alpha,5Beta)- (9Ci) is a stereochemically defined, substituted piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its specific stereochemistry is critical for biological activity and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of specialized chiral ligands used in asymmetric catalysis.
• Chemical Research: Employed in academic and industrial R&D for methodological studies in stereoselective synthesis and heterocyclic chemistry.
• Fine Chemical Production: Acts as a building block for other high-value, specialty chemicals requiring a defined piperazine core structure.

Basic Information

Product Name	Piperazine, 2,3,5-Trimethyl-, (2Alpha,3Alpha,5Beta)- (9Ci)
CAS No.	758645-85-1
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(2α,3α,5β)-2,3,5-Trimethylpiperazine; cis-2,3,5-Trimethylpiperazine; 2,3,5-Trimethylpiperazine (stereoisomer); 1,4-Diazacyclohexane, 2,3,5-trimethyl-, (2R,3R,5S)-rel-; Piperazine, 2,3,5-trimethyl-, (2α,3α,5β)-
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 2,3,5-Trimethyl-, (2Alpha,3Alpha,5Beta)- (9Ci) is produced and analyzed under strict quality management systems. We employ advanced analytical techniques including chiral HPLC, GC, and NMR to ensure stereochemical purity and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.