Description

n-Cyclohexyl 1-Boc-Piperidine-4-Carboxamide is a high-purity, protected piperidine derivative widely used as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing focused libraries and novel chemical entities in drug discovery and lead optimization.
• Peptidomimetic Synthesis: Used in the design and synthesis of peptide analogs and conformationally constrained mimetics due to its piperidine core.
• Agrochemical Development: Acts as a building block for novel crop protection agents and pesticide candidates.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP or ISO standards.

Basic Information

Product Name	n-Cyclohexyl 1-Boc-Piperidine-4-Carboxamide
CAS No.	757949-48-7
Molecular Formula	C17H30N2O3
Molecular Weight	310.44 g/mol
Synonyms	1-Boc-4-(Cyclohexylcarbamoyl)piperidine; tert-Butyl 4-[(cyclohexylamino)carbonyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(cyclohexylaminocarbonyl)piperidine; 4-Carboxamido-1-Boc-piperidine Cyclohexyl Amide; N-Cyclohexyl-1-(tert-butoxycarbonyl)piperidine-4-carboxamide; 1-Boc-piperidine-4-carboxylic acid cyclohexylamide; BOC-Piperidine-4-Carboxylic Acid Cyclohexyl Amide
EINECS	Contact for details

Quality Control

Our n-Cyclohexyl 1-Boc-Piperidine-4-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring compliance with various pharmacopeial standards and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.