Description

Piperazine, 2,3,5-Trimethyl-, (2Alpha,3Beta,5Beta)- (9Ci) is a specialized, stereochemically defined piperazine derivative with significant utility as a key chiral building block in advanced organic synthesis. Its precise three-dimensional structure makes it a valuable intermediate for the development of complex, biologically active molecules, particularly in the pharmaceutical sector. This high-purity compound is essential for research chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel APIs, especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to induce stereoselectivity in chemical reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new synthetic pathways in process chemistry.

Basic Information

Product Name	Piperazine, 2,3,5-Trimethyl-, (2Alpha,3Beta,5Beta)- (9Ci)
CAS No.	757147-87-8
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(2α,3β,5β)-2,3,5-Trimethylpiperazine; 2,3,5-Trimethylpiperazine (2α,3β,5β)-; (2R,3S,5R)-2,3,5-Trimethylpiperazine; cis-2,3,5-Trimethylpiperazine; 1,4-Diazacyclohexane, 2,3,5-trimethyl-, (2α,3β,5β)-; Piperazine, 2,3,5-trimethyl-, (2α,3β,5β)-; Chiral Trimethylpiperazine
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to confirm identity and isomeric purity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.