Description

1-[[4-(Trifluoromethoxy)Phenyl]Sulfonyl]Piperazine is a high-value, functionalized piperazine derivative characterized by its trifluoromethoxy phenyl sulfonyl group. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the introduction of specific pharmacophores and structural motifs. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the trifluoromethoxy group for enhanced bioactivity and stability.
• Chemical Research & Development: Serves as a versatile scaffold for creating novel chemical libraries and exploring structure-activity relationships (SAR).
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or functional materials requiring specific sulfonamide linkages.
• Ligand Synthesis: Can be utilized in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-[[4-(Trifluoromethoxy)Phenyl]Sulfonyl]Piperazine
CAS No.	756859-05-9
Molecular Formula	C11H13F3N2O3S
Molecular Weight	310.29 g/mol
Synonyms	1-[(4-Trifluoromethoxyphenyl)sulfonyl]piperazine; 1-(4-Trifluoromethoxybenzenesulfonyl)piperazine; 4-(Trifluoromethoxy)benzenesulfonylpiperazine; Piperazine, 1-[[4-(trifluoromethoxy)phenyl]sulfonyl]-; N-(4-Trifluoromethoxyphenylsulfonyl)piperazine; 4-(Trifluoromethoxy)phenyl piperazine-1-sulfonate; 756859-05-9
EINECS	Contact for details

Quality Control

Our 1-[[4-(Trifluoromethoxy)Phenyl]Sulfonyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.