Description

2-Pyrazinamine, 3-Nitro-, 1-Oxide (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that leverage its unique nitro- and N-oxide functionalized pyrazine core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs) due to its potential chelating sites.
• Material Science: Investigated as a building block for high-performance polymers or energetic materials where thermal stability and nitrogen content are valuable.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.

Basic Information

Product Name	2-Pyrazinamine, 3-Nitro-, 1-Oxide (9Ci)
CAS No.	754196-99-1
Molecular Formula	C4H4N4O3
Molecular Weight	156.10 g/mol
Synonyms	3-Nitro-2-pyrazinamine 1-oxide; 3-Nitro-2-aminopyrazine 1-oxide; 2-Amino-3-nitropyrazine 1-oxide; 3-Nitro-pyrazin-2-ylamine 1-oxide; 2-Pyrazinamine, 3-nitro-, N-oxide; 3-Nitro-2-pyrazinamine N-oxide; 1-Hydroxy-3-nitro-2-pyrazinamine
EINECS	Contact for details

Quality Control

Our 2-Pyrazinamine, 3-Nitro-, 1-Oxide (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of nitro and N-oxide groups, it should be stored separately from strong reducing agents and combustible materials.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.