Description

5-Chloro-2-(4-Methyl-Piperazin-1-Yl)-Phenylamine is a high-purity, advanced pharmaceutical intermediate featuring a unique piperazine-phenylamine scaffold. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules. The material is supplied with full analytical documentation to ensure consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and receptor antagonists.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds and functionalized anilines.
• Biochemical Research: Potential tool compound for probing biological pathways and enzyme interactions in vitro.
• Fine Chemical Production: Employed in the scaled-up manufacture of specialized chemicals for advanced applications.

Basic Information

Product Name	5-Chloro-2-(4-Methyl-Piperazin-1-Yl)-Phenylamine
CAS No.	747411-55-8
Molecular Formula	C11H16ClN3
Molecular Weight	225.72 g/mol
Synonyms	5-Chloro-2-(4-methylpiperazin-1-yl)aniline; 1-(4-Amino-2-chlorophenyl)-4-methylpiperazine; 2-Chloro-5-(4-methylpiperazin-1-yl)aniline; 747411-55-8; 5-Chloro-2-(4-methyl-1-piperazinyl)benzenamine; Benzenamine, 5-chloro-2-(4-methyl-1-piperazinyl)-; 5-Chloro-2-(4-methylpiperazin-1-yl)phenylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(4-Methyl-Piperazin-1-Yl)-Phenylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material traceability and consistency for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.