Description

1-Boc-2-Cyano-2-Methylpiperidine is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and fine chemical manufacturing who require reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), especially those containing piperidine or piperazine scaffolds.
• Medicinal Chemistry Research: Used in the synthesis of novel drug candidates for central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target validation.
• Peptidomimetics: Utilized to introduce constrained, non-natural amino acid analogs into peptide chains to enhance stability and bioactivity.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-Boc-2-Cyano-2-Methylpiperidine
CAS No.	746658-72-0
Molecular Formula	C12H20N2O2
Molecular Weight	224.30 g/mol
Synonyms	2-Methyl-2-(tert-butoxycarbonylamino)pentanenitrile; 1-(tert-Butoxycarbonyl)-2-cyano-2-methylpiperidine; tert-Butyl 2-cyano-2-methylpiperidine-1-carboxylate; 2-Cyano-2-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-2-cyano-2-methylpiperidine; Boc-2-cyano-2-methylpiperidine; 746658-72-0
EINECS	Contact for details

Quality Control

Our 1-Boc-2-Cyano-2-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.