Description

3-(3-Fluoro-Benzyl)-Piperidine Hydrochloride is a high-purity, fluorinated piperidine derivative offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers in the life sciences sector for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Building Block for Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its fluorinated benzyl and piperidine motifs.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agrochemical product development.
• Chemical Synthesis Reagent: Functions as a versatile intermediate in multi-step organic synthesis for creating complex molecular architectures.
• Biochemical Research: May be used in the development of biochemical probes and tools for studying biological pathways and enzyme interactions.

Basic Information

Product Name	3-(3-Fluoro-Benzyl)-Piperidine Hydrochloride
CAS No.	745817-34-9
Molecular Formula	C12H16FClN
Molecular Weight	228.72 g/mol
Synonyms	3-[(3-Fluorophenyl)methyl]piperidine hydrochloride; 3-(3-Fluorobenzyl)piperidine HCl; 1-(3-Fluorobenzyl)piperidin-3-amine hydrochloride; Piperidine, 3-[(3-fluorophenyl)methyl]-, hydrochloride (1:1); 3-(3-Fluorobenzyl)piperidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-Benzyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.