Description

1-(3-Fluoro-Benzenesulfonyl)-Piperazine is a high-purity sulfonamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a fluoro-benzenesulfonyl-piperazine moiety into complex molecular structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the biological activity of the sulfonamide group.
• Chemical Research & Development: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific sulfonamide functionalities.

Basic Information

Product Name	1-(3-Fluoro-Benzenesulfonyl)-Piperazine
CAS No.	743441-88-5
Molecular Formula	C10H13FN2O2S
Molecular Weight	244.29 g/mol
Synonyms	1-[(3-Fluorophenyl)sulfonyl]piperazine; 3-Fluoro-N-(piperazin-1-yl)benzenesulfonamide; Piperazine, 1-[(3-fluorophenyl)sulfonyl]-; 1-(3-Fluorobenzenesulfonyl)piperazine; 3-Fluorobenzenesulfonylpiperazine; 1-(3-Fluorophenylsulfonyl)piperazine; 743441-88-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) detailing specific results for parameters such as assay, related substances, and residual solvents are available upon request. We adhere to strict in-process controls to guarantee batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.